fondationvocation

Gehumaniseerd kweekmedium voor het genereren van klinische kwaliteit van

Toxiciteit van combinaties van remmers van de kinaseroute voor normale menselijke cellen in een driedimensionale cultuur

Resistance to single-agent chemotherapy and molecularly targeted drugs prevents sustained efficacy of treatments. To address this challenge, combination drug treatments have been used to improve outcomes for patients. Potential toxicity of combination treatments is a major concern, however, and has led to the failure of several clinical trials in different cancers. The use of cell-based models of normal tissues in preclinical studies enables testing and identifying toxic effects of drug combinations and facilitates an informed decision-making process for advancing the treatments to animal models and clinical trials. Recently, we established that combinations of molecular inhibitors of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase-protein kinase B (PI3K/Akt) pathways effectively and synergistically inhibit growth of BRAFmut and KRASmut colorectal tumor spheroids by blocking feedback signaling of downstream kinase pathways. These pathways are important for cell proliferation, however, and their simultaneous inhibition may cause toxicity to normal cells. We used a cellular spheroid model to study toxicities of drug combinations to human bone marrow and colon. Our results indicated that MAPK and PI3K/Akt inhibitors used simultaneously were only moderately toxic to bone marrow cells but significantly more toxic to colon cells. Our molecular analysis of proliferative cell activities and housekeeping proteins further corroborated these results. Overall, our approach to identify toxic effects of combinations of cancer drugs to normal cells in three-dimensional cultures will facilitate more informed treatment selections for subsequent animal studies.

Gehumaniseerd kweekmedium voor het genereren van klinische kwaliteit van erytroïde cellen uit navelstrengbloed CD34 cellen

 

 

Purpose: Transfusion of red blood cells (RBCs) is a supportive and common treatment in surgical care, trauma, and anemia. However, in vivo production of RBC seems to be a suitable alternative for blood transfusions due to the limitation of blood resources, the possibility of disease transmission, immune reactions, and the presence of rare blood groups. Cell cultures require serum-free or culture media supplemented with highly expensive animal serum, which can transmit xenoviruses. Platelet lysate (PL) can be considered as a suitable alternative containing a high level of growth factors and a low production cost.
 Methods: Three-step culture media supplemented with PL or fetal bovine serum (FBS) were used for proliferation and differentiation of CD34+ umbilical cord blood stem cells to erythrocytes in co-culture with bone marrow mesenchymal stem cells (BM-MSCs). The cells were cultivated for 15 days and cell proliferation and expansion were assessed using cell counts at different days. Erythroid differentiation genes, CD71 and glycophorin A expression levels were evaluated.
Results: Maximum hematopoietic stem cells (HSCs) proliferation was observed on day 15 in PL-containing medium (99±17×103-fold). Gene expression and surface markers showed higher differentiation of cells in PL-containing medium.
 Conclusion: The results of this study indicate that PL can enhance erythroid proliferation and differentiation of CD34+ HSCs. PL can also be used as a proper alternative for FBS in the culture medium and HSCs differentiation.

fondationvocation

Tetrodotoxin (TTX) ELISA Test Kit

DEIANJ48 96T
EUR 1625
Description: This test kit is for the quantitative detection of Tetrodotoxin in the tissue, liver, fish.

CA72-4 ELISA test

24 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA72-4

FERR ( Ferritin) ELISA test

7 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FERR ( Ferritin)

TSH (Thyrotrophin) ELISA test

14 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of TSH (Thyrotrophin)

T3 (Triiodothyronine) ELISA test

15 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine)

T4 (Thyroxine) ELISA test

16 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of T4 (Thyroxine)

TESTO (Testosterone) ELISA test

19 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of O (osterone)

PROG (Progesterone) ELISA test

20 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of PROG (Progesterone)

E2 (Estradiol) ELISA test

5 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of E2 (Estradiol)

PRL (Prolactin) ELISA test

4 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of PRL (Prolactin)

PreS2-Ag ELISA test

96 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of PreS2-Ag

HBcAb Sandwich ELISA test

95 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HBcAb Sandwich

Melamine Rapid Test Kit

abx092011-50tests 50 tests
EUR 370
  • Shipped within 5-12 working days.

NDV rapid test kit

RG15-03 1 box
EUR 139.05
Description: Please check the datasheet of NDV rapid test kit before using the test.

HGH (Human chorionic gonadotropin) ELISA test

22 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of HGH (Human chorionic gonadotropin)

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-20tests 20 tests
EUR 236
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-40tests 40 tests
EUR 321
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

Human toluidine Red Unheated Serum Test (TRUST) ELISA Kit

abx257506-96tests 96 tests
EUR 637
  • Shipped within 5-12 working days.

CA125 (Cancer antigen) ELISA test

11 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA125 (Cancer antigen)

CA199 (Cancer antigen) ELISA test

13 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA199 (Cancer antigen)

FT3 (Free triiodothyronine) ELISA test

17 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FT3 (Free triiodothyronine)

FT4 (Free thyroxine) ELISA test

18 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FT4 (Free thyroxine)

LH (Luteinizing Hormone) ELISA test

2 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of LH (Luteinizing Hormone)

CA153 (Cancer antigen) ELISA test

12 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA153 (Cancer antigen)

CA50 (Cancer antigen) ELISA test

10 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA50 (Cancer antigen)

AFP (Alpha fetoprotein) ELISA test

6 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of AFP (Alpha fetoprotein)

CEA (Cancer antigen) ELISA test

9 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CEA (Cancer antigen)

HAV antibody IgM ELISA test

75 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HAV antibody IgM

HEV antibody IgM ELISA test

92 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HEV antibody IgM

Melamine (MEL) Rapid Test Kit

abx092057-50tests 50 tests
EUR 370
  • Shipped within 5-12 working days.

Clenbuterol (CLE) Rapid Test Kit

abx092058-50tests 50 tests
EUR 244
  • Shipped within 5-12 working days.

Ractopamine (RAC) Rapid Test Kit

abx092059-50tests 50 tests
EUR 244
  • Shipped within 5-12 working days.

Salbutamol (SAL) Rapid Test Kit

abx092060-50tests 50 tests
EUR 244
  • Shipped within 5-12 working days.

Tetracycline (TCs) Rapid Test Kit

abx092063-50tests 50 tests
EUR 398
  • Shipped within 5-12 working days.

Sulfonamides (Sas) Rapid Test Kit

abx092064-40tests 40 tests
EUR 398
  • Shipped within 5-12 working days.

Quinolones (QNs) Rapid Test Kit

abx092065-40tests 40 tests
EUR 398
  • Shipped within 5-12 working days.

Ciprofloxacin (CPFX) Rapid Test Kit

abx092066-50tests 50 tests
EUR 398
  • Shipped within 5-12 working days.

Quinolones (QNs) Rapid Test Kit

abx092067-40tests 40 tests
EUR 398
  • Shipped within 5-12 working days.

Brucella Antibody Rapid Test Kit

abx092069-40tests 40 tests
EUR 356
  • Shipped within 5-12 working days.

PCRAgH5 AIV Detection Test Kit

PD55-02 1 kit
EUR 902.47
Description: Please check the datasheet of PCRAgH5 AIV Detection Test Kit before using the test.

Rapid Leishmania Ab Test Kit

RB2104 1 box
EUR 127
Description: Please check the datasheet of Rapid Leishmania Ab Test Kit before using the test.

Rapid PED Ag Test Kit

RG14-01 1 box
EUR 159.9
Description: Please check the datasheet of Rapid PED Ag Test Kit before using the test.

Antibody ISOTYPING TEST KIT (OKSA11303)

OKSA11303 10 Tests
EUR 780
Description: Description of target: MOUSE MONOCLONAL ANTIBODY ISOTYPING TEST KIT;Species reactivity: Mouse;Application: IS;Assay info: ;Sensitivity:

FSH (Human Follicle-stimulating hormone) ELISA test

3 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FSH (Human Follicle-stimulating hormone)

Human Echovirus (ECHO) IgM Rapid Test Kit

abx092093-20tests 20 tests
EUR 272
  • Shipped within 5-12 working days.

Human Toxoplasma (TOX) IgG Rapid Test Kit

abx092098-20tests 20 tests
EUR 217
  • Shipped within 5-12 working days.

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110
  • Category: Cas9

DNASE TEST AGAR

D04-101-10kg 10 kg Ask for price

DNASE TEST AGAR

D04-101-2Kg 2 Kg Ask for price

DNASE TEST AGAR

D04-101-500g 500 g Ask for price

DERMATOPHYTE TEST AGAR

D04-107-10kg 10 kg
EUR 849

DERMATOPHYTE TEST AGAR

D04-107-2Kg 2 Kg
EUR 224

DERMATOPHYTE TEST AGAR

D04-107-500g 500 g
EUR 97

MOTILITY TEST MEDIUM

M13-121-10kg 10 kg
EUR 1528

MOTILITY TEST MEDIUM

M13-121-2Kg 2 Kg
EUR 371

MOTILITY TEST MEDIUM

M13-121-500g 500 g
EUR 137

SNYDER TEST AGAR

S19-119-10kg 10 kg
EUR 1049

SNYDER TEST AGAR

S19-119-2Kg 2 Kg
EUR 267

SNYDER TEST AGAR

S19-119-500g 500 g
EUR 109

SAM Test Strip

TS00201s-30 30 tests
EUR 416
Description: S-adenosylmethionine quantitative test strip for serum, plasma and whole blood

SAH Test Strip

TS00301s-30 30 tests
EUR 504
Description: S-adenosylhomocysteine quantitative test strip for serum, plasma and whole blood

HCY Test Strip

TS00401s-30 30 tests
EUR 553
Description: Serum homocysteine quantitative test strip

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132
  • Category: Cas9

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)

GEN-402-25tests 25 tests
EUR 244
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 153
  • Category: Cas9

CMV (Cytomegalovirus Antibody IgM) ELISA test

29 96T/Box Ask for price
  • Area of application: Prepotency testing
Description: ELISA based test for quantitative detection of CMV (Cytomegalovirus Antibody IgM)

RV (Rubella Antibody IgG) ELISA test

30 96T/Box Ask for price
  • Area of application: Prepotency testing
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgG)

CYFRA211 (Keratin 21-1) ELISA test

23 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CYFRA211 (Keratin 21-1)

IAA (Anti-insulin antibody) ELISA test

25 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of IAA (Anti-insulin antibody)

IgE (Immune globulin E) ELISA test

21 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of IgE (Immune globulin)

RV (Rubella Antibody IgM) ELISA test

31 96T/Box Ask for price
  • Area of application: Prepotency testing
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgM)

CMV (Cytomegalovirus Antibody IgG) ELISA test

28 96T/Box Ask for price
  • Area of application: Prepotency testing
Description: ELISA based test for quantitative detection of CMV (Cytomegalovirus Antibody IgG)

TOX (Toxoplasma Antibody IgM) ELISA test

33 96T/Box Ask for price
  • Area of application: Prepotency testing
Description: ELISA based test for quantitative detection of TOX (Toxoplasma Antibody IgM)

TOX (Toxoplasma Antibody IgG) ELISA test

32 96T/Box Ask for price
  • Area of application: Prepotency testing
Description: ELISA based test for quantitative detection of TOX (Toxoplasma Antibody IgG)

ACA (Anticardiolipin Antibody IgA) ELISA test

61 96T/Box Ask for price
  • Area of application: Immunological infertility
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgA)

ANA (Antinuclear Antibody IgG) ELISA test

52 96T/Box Ask for price
  • Area of application: Rheumatic diseases
Description: ELISA based test for quantitative detection of ANA (Antinuclear Antibody IgG)

ACA (Anticardiolipin Antibody IgG) ELISA test

59 96T/Box Ask for price
  • Area of application: Immunological infertility
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgG)

ACA (Anticardiolipin Antibody IgM) ELISA test

60 96T/Box Ask for price
  • Area of application: Immunological infertility
Description: ELISA based test for quantitative detection of ACA (Anticardiolipin Antibody IgM)

Adv (Adenovirus Antibody IgM) ELISA test

44 96T/Box Ask for price
  • Area of application: Respiratory tract testing
Description: ELISA based test for quantitative detection of Adv (Adenovirus Antibody IgM)

PSA (Prostate-specific antigen) ELISA test

8 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of PSA (Prostate-specific antigen)

Syphilis anti-TP syphilis ELISA test

99 96T/Box Ask for price
  • Area of application: Blood Screening
Description: ELISA based test for quantitative detection of Syphilis anti-TP syphilis

HPV (Human Papilloma Virus Antibody IgG) ELISA test

49 96T/Box Ask for price
  • Area of application: Sexually transmitted diseases
Description: ELISA based test for quantitative detection of HPV (Human Papilloma Virus Antibody IgG)

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 4941
  • Category: PinPoint Integrase Tools

Clenbuterol Rapid Test Kit (Colloidal gold)

abx092040-50tests 50 tests
EUR 272
  • Shipped within 5-12 working days.

Ractopamine Rapid Test Kit (Colloidal gold)

abx092042-50tests 50 tests
EUR 300
  • Shipped within 5-12 working days.

Salbutamol Rapid Test Kit (Colloidal gold)

abx092043-50tests 50 tests
EUR 342
  • Shipped within 5-12 working days.

Chloramphenicol Rapid Test Kit (Colloidal gold)

abx092045-50tests 50 tests
EUR 356
  • Shipped within 5-12 working days.

Quinolones Rapid Test Kit (Colloidal gold)

abx092046-50tests 50 tests
EUR 537
  • Shipped within 5-12 working days.

Sulfonamides Rapid Test Kit (Colloidal gold)

abx092047-50tests 50 tests
EUR 551
  • Shipped within 5-12 working days.

Tetracycline Rapid Test Kit (Colloidal gold)

abx092048-50tests 50 tests
EUR 467
  • Shipped within 5-12 working days.

Zearalenone Rapid Test Kit (Colloidal gold)

abx092051-50tests 50 tests
EUR 411
  • Shipped within 5-12 working days.

Deoxynivalenol Rapid Test Kit (Colloidal gold)

abx092052-50tests 50 tests
EUR 467
  • Shipped within 5-12 working days.

Deoxynivalenol Rapid Test Kit (Colloidal gold)

abx092053-50tests 50 tests
EUR 467
  • Shipped within 5-12 working days.

Aflatoxin Rapid Test Kit (Colloidal gold)

abx092054-50tests 50 tests
EUR 398
  • Shipped within 5-12 working days.

Zearalenone Rapid Test Kit (Colloidal gold)

abx092056-50tests 50 tests
EUR 425
  • Shipped within 5-12 working days.

Goat Brucella Antibody Rapid Test Kit

abx092070-40tests 40 tests
EUR 356
  • Shipped within 5-12 working days.

Cow Brucella Antibody Rapid Test Kit

abx092071-40tests 40 tests
EUR 356
  • Shipped within 5-12 working days.

Pig Parvovirus Antibody Rapid Test Kit

abx092074-50tests 50 tests
EUR 321
  • Shipped within 5-12 working days.

Anigen Rapid FIV Ab Test Kit

RB22-01-DD 10 tests/Kit
EUR 129.8
Description: Please check the datasheet of Anigen Rapid FIV Ab Test Kit before using the test.

Rapid Bovine Brucella Ab Test Kit

RB23-01-DD 1 kit/10 tests
EUR 151.79
Description: Please check the datasheet of Rapid Bovine Brucella Ab Test Kit before using the test.

Rapid Bovine TB Ab Test Kit

RB23-02-DD 1 box
EUR 128.4
Description: Please check the datasheet of Rapid Bovine TB Ab Test Kit before using the test.

Rapid FMD NSP Ab Test Kit

RB28-02-DD 1 box
EUR 135.4
Description: Please check the datasheet of Rapid FMD NSP Ab Test Kit before using the test.

AgRapidFeLV Ag/FIV Ab Test Kit

RC12-04 10 tests/kit
EUR 170.4
Description: Please check the datasheet of AgRapidFeLV Ag/FIV Ab Test Kit before using the test.

Ag rapid CDV Ag Test Kit

RG11-03 1 box
EUR 138.2
Description: Please check the datasheet of Ag rapid CDV Ag Test Kit before using the test.

Rapid TGE/PED Ag Test Kit

RG14-03 1 box
EUR 240.85
Description: Please check the datasheet of Rapid TGE/PED Ag Test Kit before using the test.

Ag Rapid AIV Ag Test Kit

RG15-01 1 box/30 tests
EUR 267
Description: Please check the datasheet of Ag Rapid AIV Ag Test Kit before using the test.

Ag Rapid H5AIV Ag test kit

RG15-05 1 box
EUR 463
Description: Please check the datasheet of Ag Rapid H5AIV Ag test kit before using the test.

Rat Antibody ISOTYPING TEST KIT (OKSA11304)

OKSA11304 10 Tests
EUR 924
Description: Description of target: RAT MONOCLONAL ANTIBODY ISOTYPING TEST KIT;Species reactivity: Rat;Application: IS;Assay info: ;Sensitivity:

Human Hepatitis A Virus IgG Rapid Test Kit

abx092012-25tests 25 tests
EUR 425
  • Shipped within 5-12 working days.

Human Chlamydia Pneumoniae (CP) IgG Rapid Test Kit

abx092079-20tests 20 tests
EUR 258
  • Shipped within 5-12 working days.

Human Chlamydia Pneumoniae (CP) IgM Rapid Test Kit

abx092080-20tests 20 tests
EUR 258
  • Shipped within 5-12 working days.

Human Mycoplasma Pneumoniae (MP) IgG Rapid Test Kit

abx092081-20tests 20 tests
EUR 258
  • Shipped within 5-12 working days.

Human Mycoplasma Pneumoniae (MP) IgM Rapid Test Kit

abx092082-20tests 20 tests
EUR 258
  • Shipped within 5-12 working days.

Human Mycobacterium Tuberculosis (MT) IgG Rapid Test Kit

abx092084-20tests 20 tests
EUR 230
  • Shipped within 5-12 working days.

Human Helicobacter Pylori (HP) IgG Rapid Test Kit

abx092090-20tests 20 tests
EUR 230
  • Shipped within 5-12 working days.

Human Enterovirus 71 (EV71) IgM Rapid Test Kit

abx092091-20tests 20 tests
EUR 342
  • Shipped within 5-12 working days.

Human Hantavirus (HV) IgM / IgG Rapid Test Kit

abx092094-20tests 20 tests
EUR 272
  • Shipped within 5-12 working days.

Human Streptococcus Pneumoniae (SP) Antigen Rapid Test Kit

abx092096-20tests 20 tests
EUR 398
  • Shipped within 5-12 working days.

Human Rubella Virus (RV) IgG Rapid Test Kit

abx092097-20tests 20 tests
EUR 217
  • Shipped within 5-12 working days.

Human Rabies Virus (HRV) IgG Rapid Test Kit

abx092100-20tests 20 tests
EUR 342
  • Shipped within 5-12 working days.

Human Treponema Pallidum (TP) Antibody Rapid Test Kit

abx092101-20tests 20 tests
EUR 258
  • Shipped within 5-12 working days.

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 4941
  • Category: PinPoint Integrase Tools

AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE620A-KIT 1 kit
EUR 2132
  • Category: Gene Editing

Basic Cytotoxicity Test Kits

CT17001 125 Tests
EUR 409

Basic Cytotoxicity Test Kits

CT17002 250 Tests
EUR 650

Total Cytotoxicity Test Kits

CT17003 125 Tests
EUR 513

Total Cytotoxicity Test Kits

CT17004 250 Tests
EUR 813

Clearview Chlamydia MF test

CV504524 1 box
EUR 162
Description: Please check the datasheet of Clearview Chlamydia MF test before using the test.

IBD rapid test strip

RG15-04 10 boxes
EUR 148
Description: Please check the datasheet of IBD rapid test strip before using the test.

Rabies rapid test strip

RG18-01 10 boxes
EUR 151.92
Description: Please check the datasheet of Rabies rapid test strip before using the test.

AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE622A-KIT 1 kit
EUR 2132
  • Category: Gene Editing

AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE624A-KIT 1 kit
EUR 2132
  • Category: Gene Editing

HCG?Anti-Human Chorionic Gonadotrophin Antibody IgM) ELISA test

66 96T/Box Ask for price
  • Area of application: Immunological infertility
Description: ELISA based test for quantitative detection of HCG?Anti-Human Chorionic Gonadotrophin Antibody IgM)

Moleculaire cytogenetische analyse en het opzetten van een celkweek bij de vissoort Hollandichthys multifasciatus (Eigenmann & amp; Norris, 1900) (Characiformes, Characidae)

Hollandichthys is a fish genus of the family Characidae that was until recently considered to be monotypic, with cytogenetic, morphological, and molecular data being restricted to a few local populations. In the present study, the karyotype of a population of Hollandichthys multifasciatus was analyzed using classical and molecular cytogenetic approaches for the investigation of potential markers that could provide new perspectives on the cytotaxonomy. H. multifasciatus presented a diploid number of 2n=50 chromosomes and a karyotype formula of 8m+10sm+32st. A single pair of chromosomes presented Ag-NORs signals, which coincided with the 18S rDNA sites visualized by FISH, whilst the 5S rDNA sequences were mapped in two chromosome pairs. The distribution of the U snRNA genes was mapped on the Hollandichthys chromosomes for the first time, with the probes revealing the presence of the U1 snDNA on the chromosomes of pair 20, U2 on pairs 6 and 19, U4 on pair 16, and U6 on the chromosomes of pair 11. The results of the present study indicated karyotypic differences in comparison with the other populations of H. multifasciatus studied previously, reinforcing the need for further research to identify isolated populations or the potential existence of cryptic Hollandichthys species.
• The effects of salt stress and adaptation on salicylic acid (SA) content and on antioxidant and lipoxygenase (LOX) enzyme activities were studied in tomato (Lycopersicon esculentum cv. Pera) cells. • NaCl-adapted cells were obtained from calli adapted to 100 mm NaCl by successive subcultures in medium supplemented with 100 mm NaCl. Salt stress treatments consisted of the addition of 100 mm NaCl to cells. • Adapted cells contained a lower concentration of SA than unadapted cells. The lower manganese-containing superoxide dismutase (Mn-SOD) and LOX activities as well as the higher glutathione reductase (GR) and ascorbate peroxidase (APX) activities in adapted cells than in unadapted cells could be correlated with the development of salt adaptation. Salt stress increased APX and LOX activities as well as lipid peroxidation in unadapted cells and increased Mn-SOD activity in both types of cells. Application of 200 µm SA + 100 mm NaCl inhibited APX activity in both unadapted and adapted cells, induced the Mn-SOD in adapted cells and increased lipid peroxidation in unadapted cells. • Our data indicate that adaptation of tomato cells to NaCl results in a higher tolerance to NaCl-induced oxidative stress and suggest a role for SA in this response.

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